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63 Furthermore, BCAT 1 is selectively upregulated in isocitrate dehydrogenase (IDH) wild-type (WT) GBM, and -ketoglutarate (-KG) mediates cell death in BCAT 1-deficient IDH WT GBM

Ciji A, Akhtar MS

Antioxidants 10 , 43 (2020)

References 1 TannahillGMCurtisAMAdamikJPalsson-McDermottEMMcGettrickAFGoelGet al

Clinical trials have demonstrated significant weight loss (mean 1015% body weight reduction) in individuals with obesity when combined with lifestyle interventions [1] [5]

LCP NPs loaded with the modified tumor-specific BRAF-mutant peptide were effectively activate advanced BRAF-specific immune response as well as a significant increase in IFN- production